On April 11, the 4th Traditional Chinese Medicine Anti-Aging Conference opened at the Internet International Exhibition Center in Wuzhen, Zhejiang. The conference was themed "Scientific Anti-Aging and Unlocking the Health and Longevity Code", and brought together academicians of the Chinese Academy of Engineering and experts and scholars from home and abroad to discuss the cutting-edge progress and future picture of anti-aging research. Professor Jia Zhenhua from Hebei Provincial Institute of Lianxue Innovation Medicine gave a theme report at the conference with the title "Research on the Anti-aging of Traditional Chinese Medicine by Guiding the Theory of Qi and Luxue Theory".

On April 11, Professor Jia Zhenhua from Hebei Provincial Institute of Luxury Innovation Medicine gave a theme report at the 4th Traditional Chinese Medicine Anti-Aging Conference

Aging has become a frontier and hot topic of attention in the world's life sciences field

Jia Zhenhua pointed out that premature aging and aging-related diseases seriously affect lifespan and health. In the 2017 Global Burden of Disease Study, 92 of the 293 diseases (31.4%) were determined to be related to age-added, the most important of which are heart disease, stroke, Alzheimer's disease, diabetes, COPD, chronic kidney disease and cancer, and about 50% of the mortality rate is attributed to aging-related diseases.

The International Classification of Diseases (2018) officially announced that aging is a curable disease.

Jia Zhenhua emphasized that traditional Chinese medicine provides original thinking to seize the international commanding heights of anti-aging, give full play to the advantages of traditional Chinese medicine, and actively promote scientific research and innovation in anti-aging of traditional Chinese medicine to awaken the public's health awareness, spread health knowledge, and provide health services.

The core of traditional Chinese medicine anti-aging theory is "spiritual spirit"

"How to explore the prevention and treatment strategies of these diseases from the perspective of aging? It is an important part of our anti-aging research." Jia Zhenhua said that the word aging should be read separately. "Old" means digital age, and "decline" means "weakness and exhaustion". "Aging before ageing" and "aging without aging" refer to physiological age, also known as biological age. "Enjoy your age and leave after a hundred years" is the pursuit of human health and longevity. To achieve "rejuvenation of the elderly", it is urgent to build a new anti-aging theory of traditional Chinese medicine and seek effective intervention strategies and drugs.

Academician Wu Yiling's expert team believes that essence is the origin of life, qi is the driving force of life, and spirit is the embodiment of life, and proposed the core pathogenesis of aging - deficiency of kidney essence is the foundation of aging, deficiency of vital energy is the key to aging, and loss of body and spirit is the manifestation of aging. Therefore, the key to anti-aging is to nourish the kidneys and fill the essence, warm the vitality, and nourish the body and spirit. The theory of Qi and Lian theory has been systematically constructed to guide the anti-aging research of traditional Chinese medicine.

Experiments have confirmed that Bazi nourishes the kidney and prolongs the lifespan of naturally aged animals, reduces the death of stress-aging animals, and prevents and treats elderly diseases caused by aging.

In recent years, under the guidance of the theory of Qiluo theory, Academician Wu Yiling has conducted systematic research on the kidney-tonifying prescriptions for more than two thousand years, and inherited and innovatively developed Bazi Shen-tonifying Capsules.

"This medicine uses eight kidney-tonifying seed medicines, including Cuscuta, wolfberry, and Schisandra chinensis as the core of the prescription." Professor Jia Zhenhua said, "A seed can germinate and grow into a towering tree. The seed medicine has the strongest vitality and the ingredients contained are also related to anti-aging. On this basis, the raw Rehmannia huang nourishes kidney yin, epimedium, etc. to help kidney yang, and ginseng supports vital energy. The comprehensive replenishment of kidney and essence is nourished, regulating yin and yang, warming and nourishing vital energy, nourishing body and spirit, which is completely in line with the theory of essence, energy and spirit."

Jia Zhenhua shared a series of major progress in the anti-aging research of traditional Chinese medicine Bazi Bushen Capsules, which delay aging through eight ways, including improving intercellular communication, regulating epigenetics, reducing telomere depletion, and maintaining mitochondrial homeostasis. It can extend the lifespan of naturally aging animals, reduce the death of stress-aging animals, and prevent and treat elderly diseases caused by aging.

"Through experimental research, Bazi nourishes the kidney can significantly increase the length of telomeres and improves telomerase activity, which inhibits the process of aging from this mechanism. Mitochondria is the energy factory of humans. Bazi nourishes the kidney can maintain the homeostasis of mitochondria, reduce mitochondria damage, and improve the function of mitochondria. The smallest unit of a human is cells. Bazi nourishes the kidney can slow down the aging rate of cells and achieve prolong lifespan." Jia Zhenhua introduced that relevant research also shows that in addition to delaying overall aging, Bazi Bushen Capsules have a systematic intervention and comprehensive anti-aging effect on the function of nine major systems such as nerves, movement, circulation, breathing, digestion, immunity, reproduction, and skin.

The first randomized, double-blind, multi-center, placebo-controlled clinical study confirms the breakthrough of Bazi kidney tonifying and anti-aging

Xiyuan Hospital of the Chinese Academy of Traditional Chinese Medicine led 8 clinical centers to carry out "Bazi Bushen Capsules Anti-aging Randomized, Double-Blind, Placebo-controlled, Multi-Center Clinical Research". The study was selected as participants who met the Chinese medicine kidney essence deficiency syndrome and had the relevant symptoms scores in compliance with the requirements. The clinical value of Bazi Bushen Capsules in anti-aging was comprehensively and objectively evaluated through indicators such as the kidney essence deficiency core symptoms scale and the related weakness assessment scale.

Clinical evidence-based research has confirmed that Bazi Bushen Capsules can significantly improve the aging symptoms of aging population, improve physical and psychological aging status, improve quality of life, enhance the exercise ability and endurance of the elderly, showing the unique advantages of traditional Chinese medicine in the field of anti-aging.

Jia Zhenhua said that the world's advanced anti-aging laboratory has been established and has an authoritative expert team. The current research results have proved that traditional Chinese medicine does have its unique advantages in anti-aging. Compared with the world's research level, this research should still be at the forefront.

At the "Experts Conference on Anti-aging Research of Bazi Bushen Capsules for the Qiluo Theory Guidance of the Bazi Bushen Capsules" organized by the World Federation of Traditional Chinese Medicine Society, the expert's argumentation opinions pointed out that for the first time, the theory of the essence, Qiluo Theory was constructed, forming a new idea for anti-aging research; the patented Chinese medicine Bazi Bushen Capsules has been developed, which has the anti-aging effects of nourishing the kidneys and filling essence, regulating yin and yang, warming the vital energy, and nourishing the body and spirit, and is expected to become a representative Chinese patent medicine for anti-aging in traditional Chinese medicine. These studies combine traditional traditional Chinese medicine theory innovation with modern science and technology, and have made significant progress in the anti-aging research of traditional Chinese medicine, produced important original results, and laid a solid foundation for future in-depth research.

Relying on the national key R&D plan, the World Zhonglian released the first "Traditional Medicine Intervention and Expert Consensus for Aging"

It is reported that Jia Zhenhua is presided over the "Research on the Evaluation Technology and Integration Mechanism of the Anti-aging of Traditional Chinese Medicine" project of the National Key R&D Program Project "Traditional Medicine Modernization" "Research on the Evaluation Technology and Integration Mechanism of Qi and Guidance of the Chinese Medicine Anti-aging Evaluation" and focuses on aging diseases such as the heart, lung, brain, bone, muscle, etc., to establish a variety of aging models and multi-level evaluation systems, determine the best time and space window for intervention of traditional Chinese medicine anti-aging through multiple systems, multiple tissues, and multiple organs, to explore the biological mechanism of anti-aging of traditional Chinese medicine, to reveal the biological basis of the core pathogenesis of aging, and to open up new ways for traditional Chinese medicine to intervene in geriatric diseases. Professor Jia Zhenhua pointed out that this project is the only major scientific research plan for anti-aging in traditional Chinese medicine, leading traditional Chinese medicine to occupy the international commanding heights of anti-aging.

[Editor in charge: Sun Hui]