On April 11, the 4th Traditional Chinese Medicine Anti-Aging Conference, co-organized by the World Federation of Traditional Chinese Medicine Society, China Anti-Aging Promotion Association, and China Over-the-Counter Drug Association, was held in Wuzhen, Zhejiang. At the meeting, Professor Bian Yuhong from Tianjin University of Traditional Chinese Medicine gave an academic report entitled "Research on the Mechanisms of Compound Traditional Chinese Medicine to Suppress bone aging and improve skin aging by regulating stem cells", and shared the latest research progress in the innovative Chinese medicine Bazi Bushen Capsule delaying osteoporosis and skin aging by regulating stem cells, which attracted widespread attention from experts and scholars attending the meeting.

Professor Bian Yuhong from Tianjin University of Traditional Chinese Medicine gave an academic report at the meeting

Bian Yuhong said that the kidney is the foundation of nature and runs through all aspects of human growth, strength, old age and old. As we grow older, the kidney essence is gradually consumed, resulting in a decline in the body's functions, showing a decline in physical strength, memory loss, and a series of aging phenomena such as whitening hair and osteoporosis. Before the report began, she specifically reminded that many people think that it is to strengthen the aphrodisiac when they mention kidney nourishment. In fact, this is a misunderstanding. Traditional Chinese medicine's kidney essence nourishment emphasizes the regulation of functional state on the basis of the overall basis, maintaining the normal function of the internal organs, and allowing the body to reach a balanced state to delay the occurrence of diseases.

Bazi nourishes the kidney to increase bone density and strength and reshapes "hard bones"

As women get older, especially after menopause, their bones and muscles will be lost rapidly, which can easily cause osteoporosis and weakness in the waist and legs. Therefore, there are many cases of fractures caused by falls and fractures in the elderly in life. Many elderly people hope to relieve osteoporosis through calcium supplementation, but in fact it is far from enough. Traditional Chinese medicine believes that: the kidney controls the bones and sufficient kidney essence can better absorb calcium in the blood and deposit it into the bones; on the other hand, deficiency of kidney essence will lead to impairment of the reabsorption function of the renal tubules and increased excretion of urinary calcium, so calcium supplementation is also necessary to nourish kidney essence.

Bian Yuhong pointed out that osteoporosis is a systemic bone disease characterized by low bone mass and damage to the bone microstructure, resulting in increased bone fragility and prone to fractures. It seriously endangers the health of middle-aged and elderly people. The aging of bone marrow mesenchymal stem cells (BMSCs) is an important cause of osteoporosis. Traditional Chinese medicine does not have the disease name for senile osteoporosis, but according to its symptoms and pathogenesis, it can be classified as "bone impotence" and "bone numbness". "Bone collateral damage" is a key link in bone numbness. Bone numbness is a disease that causes kidney essence deficiency, bone collateral damage, and bone marrow impotence due to various reasons. In traditional Chinese medicine, the kidneys are responsible for bones and marrow production, and are generally treated with the rules of nourishing the kidneys and nourishing essence. Traditional Chinese medicine can regulate BMSCs affecting osteoporosis. Research has found that Bazi Bushen Capsules can improve the content of osteogenic proteins and aging-related proteins, improve the imbalance of osteogenic and lipid differentiation of BMSCs, thereby improving the bone density, bone mineral content, as well as the morphology and structure of bone trabecular bone in SAMP6 (rapid aging model) mice, and delaying the occurrence of osteoporosis.

Similarly, research from Beijing University of Traditional Chinese Medicine confirmed that Bazi kidney nourishing can significantly increase the mineral content in the bones, thereby improving the composition of bone materials. Compared with the aging group, the limit load of the bones of mice in the Bazi kidney-tonifying group increased by about 30%, indicating that Bazi kidney-tonifying can improve bone strength. The research results were published in the Chinese Journal of Osteoporosis. Bazi kidney tonic is also listed as a recommended drug by the "Guidelines for Combination of Diagnosis and Treatment of Diagnosis and Osteoporosis".

When the bones become stronger, not only will the physical strength be enhanced, but the symptoms such as soft waist and knees are improved, and the risk of falling and fractures is also lower.

Bazi kidney tonify the kidney can activate skin stem cells and enjoy a "young state"

Skin aging often manifests as wrinkles, sagging, and color spots. The core reason for these problems is collagen loss. This process is driven by endogenous (such as insufficient collagen synthesis, accelerated degradation, etc.) and exogenous factors (such as ultraviolet-induced photoaging). It not only affects physical health, but also affects the overall mental state, and has a negative impact on the psychological and social life of middle-aged and elderly people.

Regarding skin aging, Bian Yuhong pointed out that it is mainly related to skin homeostasis, and the biomarker of epidermal stem cells COL17A1 protein plays an important role in skin homeostasis. Tianjin University of Traditional Chinese Medicine found that Bazi kidney nourishing can coordinate skin homeostasis by improving oxidative stress, apoptosis, autophagy in skin tissues, and interfering with epidermal stem cells, significantly interfering with the thickness of the skin dermis and collagen fiber content of experimental animals, further improving skin aging and fur shedding.

It is reported that during the clinical evidence-based research conducted by Xiyuan Hospital of the Chinese Academy of Chinese Medical Sciences and eight clinical centers, the Key Laboratory of China Light Industry Cosmetics of Beijing Institute of Technology and Commerce also used the most advanced equipment in China to detect the hair status of the subjects in the skin. It was found that after taking Bazi tonify the kidney for 3 months, people's hair loss and wrinkles were significantly improved, and the skin and hair were also shiny, which means that the drug can protect the skin and improve people's energy and mental state as a whole.

[Editor in charge: Wu Qilong]